Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP10 | P09238 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28489905 | 0.87 | PKM (0.49) | CA1CA2KMT2AMEN1GAA | |
| SCHEMBL28493442 | 0.85 | KMT2A (0.49) | MAPTKMT2AMEN1GAAHPGD | |
| SCHEMBL28487989 | 0.82 | MAPT (0.54) | MAPTKMT2AMEN1GAAHPGD | |
| SCHEMBL28498697 | 0.82 | KMT2A (0.44) | KMT2AMEN1EDNRAGAAHPGD | |
| SCHEMBL28509158 | 0.82 | CA1 (0.45) | MAPTCA1CA2KMT2AMEN1 | |
| SCHEMBL28498454 | 0.77 | MAPT (0.43) | MAPTKMT2AMEN1GAAHPGD | |
| SCHEMBL28509136 | 0.76 | ALDH1A1 (0.56) | MAPTKMT2AKDM4ELMNAPOLB | |
| SCHEMBL28497515 | 0.73 | LMNA (0.48) | MAPTCA1CA2KMT2AMMP7 | |
| SCHEMBL28491357 | 0.72 | KMT2A (0.42) | MAPTKMT2AMEN1EDNRAGAA | |
| SCHEMBL8906392 | 0.70 | EDNRB (0.52) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110932-B | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112110932-A | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |