Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HTR7 | P34969 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 5/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480462 | 1.00 | MAPT (0.51) | MAPTHTR7LMNAGAAALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27737428 | 0.87 | MAPT (0.41) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL23997432 | 0.86 | MAPT (0.48) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL30336949 | 0.86 | MAPT (0.48) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3541135 | 0.84 | MAPK1 (0.49) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8589619 | 0.83 | ADRB1 (0.61) | HTR7ALDH1A1ADRB1SIRT6HTR1A | |
| SCHEMBL6663091 | 0.83 | MAPT (0.52) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL7374611 | 0.82 | HTR7 (0.51) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL9059492 | 0.82 | ALDH1A1 (0.52) | MAPTLMNAGAAALDH1A1CYP1A2 | |
| SCHEMBL31321242 | 0.78 | ALDH1A1 (0.43) | MAPTLMNAGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041300-B | Indole and benzimidazole derivatives as dual 5-HT2A and 5-HT6 receptor antagonists | 阿达梅德制药公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-112041300-A | Indole and benzimidazole derivatives as dual 5-HT2A and5-HT 6receptor antagonists | 阿达梅德制药公司 | 2020-12-04 | — | — | CN | disclosed |