Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471909 | 0.89 | HTT (0.54) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL29876153 | 0.85 | HTR7 (0.60) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL113133 | 0.85 | HTR7 (0.60) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL8589619 | 0.84 | ADRB1 (0.61) | HTR7ALDH1A1ADRB1SIRT6TSHR | |
| Hydrochloric Acid SCHEMBL29947196 | 0.84 | MAPT (0.59) | MAPTHTR7LMNAGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL15821250 | 0.84 | MAPT (0.59) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL28501237 | 0.83 | MAPT (0.51) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL7374611 | 0.83 | HTR7 (0.51) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL30480462 | 0.83 | MAPT (0.51) | MAPTHTR7LMNAGAAALDH1A1 | |
| SCHEMBL12128754 | 0.81 | MAPT (0.52) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082138-B1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | UNIV TEXAS (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6207660-B1 | Texaphyrin conjugates and uses thereof | PHARMACYCLICS, INC. | 2001-03-27 | — | — | US | disclosed |
| EP-1082138-A1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999062551-A1 | TEXAPHYRIN CONJUGATES AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-12-09 | — | — | WO | disclosed |