Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926984 | 0.89 | P2RX7 (0.55) | ALDH1A1MAPTMAPK1GAAMAPK14 | |
| SCHEMBL2924918 | 0.85 | P2RX7 (0.44) | ALDH1A1MAPTMAPK1GAAMAPK14 | |
| SCHEMBL2856642 | 0.85 | HPGD (0.63) | MAPK1POLBMAPK14 | |
| SCHEMBL1403180 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1GAAMAPK14 | |
| SCHEMBL2856262 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL2852950 | 0.80 | MAPK14 (0.67) | ALDH1A1MAPTPOLBMAPK14LMNA | |
| SCHEMBL2854158 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL13793890 | 0.79 | MCHR1 (0.57) | — | |
| SCHEMBL2856945 | 0.78 | ALDH1A1 (0.81) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL773204 | 0.77 | NR4A3 (0.78) | ALDH1A1MAPTMAPK1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |