Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | FPR1 | P21462 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1402778 | 0.90 | HSD11B1 (0.72) | ALDH1A1MAPTMAPK1GAAHSD11B1 | |
| SCHEMBL1403425 | 0.89 | HSD11B1 (0.56) | ALDH1A1MAPTMAPK1GAAHSD11B1 | |
| SCHEMBL15889273 | 0.87 | POLB (0.58) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL18016194 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL2850148 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL1402961 | 0.84 | HSD11B1 (0.57) | ALDH1A1MAPTMAPK1GAAHSD11B1 | |
| SCHEMBL316233 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTMAPK1GAAHSD11B1 | |
| SCHEMBL2854511 | 0.82 | SPR (0.64) | MAPK1HSD11B1FPR1POLBCNR2 | |
| SCHEMBL2857348 | 0.81 | SPR (0.54) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL316737 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTMAPK1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |