Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424187 | 0.82 | HDAC6 (0.66) | HDAC1HDAC6HDAC3NCOR2HDAC8 | |
| SCHEMBL15955801 | 0.82 | PLK1 (0.66) | HDAC6HDAC8HDAC2NR1H4HSD17B10 | |
| SCHEMBL3203482 | 0.80 | CA2 (0.50) | HDAC6HDAC8NR1H4HSD17B10EPHX2 | |
| SCHEMBL3673435 | 0.79 | HDAC6 (0.75) | HDAC1HDAC6HDAC3NCOR2HDAC8 | |
| SCHEMBL69614 | 0.79 | CA2 (0.79) | HSD17B10CA2CAMK2A | |
| SCHEMBL1577530 | 0.78 | CA2 (0.58) | NR1H4ALOX15HSD17B10EPHX2CA2 | |
| SCHEMBL20424311 | 0.78 | HDAC6 (0.67) | HDAC1HDAC6HDAC3NCOR2HDAC8 | |
| SCHEMBL276932 | 0.78 | CA2 (0.62) | HSD17B10CA2CAMK2A | |
| SCHEMBL5020665 | 0.78 | HDAC1 (1.00) | HDAC1HDAC6HDAC3NCOR2HDAC8 | |
| SCHEMBL12850618 | 0.78 | HDAC1 (0.79) | HDAC1HDAC6HDAC3NCOR2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930589-A | Tricyclic compound, pharmaceutical composition and application | 广州国家实验室 | 2025-05-06 | — | — | CN | disclosed |
| CN-119661474-A | Double-target compound derivative of hydroxamic acid and application thereof | 中国药科大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-112004813-B | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117736192-A | PI3K/HDAC dual inhibitor and application thereof | 安徽中医药大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-112004813-A | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2020-11-27 | — | — | CN | disclosed |