SCHEMBL3203482

SCHEMBL3203482

N=C(NO)c1ccc(CC(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.50
CAMK2A Q9UQM7 1/20 0.50
AKR1B1 P15121 1/20 0.48
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
ABCC4 O15439 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
TSHR P16473 1/20 0.47
PTGS1 P23219 1/20 0.47
HTT P42858 1/20 0.47
SRD5A2 P31213 2/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
NR1H4 Q96RI1 4/20 0.45
MEP1B Q16820 1/20 0.45
F2 P00734 1/20 0.44
PLG P00747 1/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584811 0.83 CA2 (0.52) CA2ITGB3ITGA2BF2PLG
SCHEMBL11681593 0.83 CA2 (0.48) CA2CAMK2AAKR1B1ITGB3ITGA2B
SCHEMBL3086516 0.80 CYP4F2 (0.54) LMNAGAAKMT2AKDM4EALDH1A1
SCHEMBL21903097 0.80 HDAC6 (0.43) LMNAHTTKMT2AMEN1F2
SCHEMBL11681760 0.80 NR1H4 (0.48) CA2CAMK2AAKR1B1ITGB3ITGA2B
SCHEMBL28501530 0.80 HDAC1 (0.63) CA2CAMK2ANR1H4EPHX2HSD17B10
SCHEMBL6393860 0.77 HDAC6 (0.74) CA2LMNAGAAKMT2AMEN1
SCHEMBL4403830 0.77 TSHR (0.57) CA2TSHRSRD5A2MEP1BALDH1A1
SCHEMBL3087853 0.76 CYP4Z1 (0.54) LMNATSHRHTTKMT2AMEN1
SCHEMBL7444750 0.76 ALDH1A1 (0.47) LMNAGAATSHRHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606548-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2026-04-21 US disclosed
US-20240166638-A1 FUNGICIDAL OXADIAZOLES FMC CORP (US) 2024-05-23 US disclosed
CN-118047729-A Fungicidal oxadiazoles FMC公司 2024-05-17 CN disclosed
CN-118047771-A Fungicidal oxadiazoles FMC公司 2024-05-17 CN disclosed
CN-110650956-B Fungicidal oxadiazoles FMC公司 2024-03-08 CN disclosed
EP-4262396-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION (US) 2023-10-25 EP disclosed
CN-116634874-A Fungicidal oxadiazoles and mixtures thereof FMC公司 2023-08-22 CN disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 US disclosed
WO-2022133114-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION (US) 2022-06-23 WO disclosed
EP-3957636-A1 FUNGICIDAL OXADIAZOLES FMC Corporation (US) 2022-02-23 EP disclosed
US-20100063108-A1 Pyridin-4-yl derivatives as immunomodulating agents ACTELION PHARMACEUTICALS LTD. (CH) 2010-03-11 US disclosed
US-20100063108-A1 Pyridin-4-yl derivatives as immunomodulating agents ACTELION PHARMACEUTICALS LTD. (CH) 2010-03-11 US disclosed
EP-2125797-A1 AMINO- PYRIDINE DERIVATIVES AS S1P1 /EDG1 RECEPTOR AGONISTS Actelion Pharmaceuticals Ltd. (CH) 2009-12-02 EP disclosed
EP-2069336-A1 PYRIDIN-4-YL DERIVATIVES AS IMMUNOMODULATING AGENTS Actelion Pharmaceuticals Ltd. (CH) 2009-06-17 EP disclosed
EP-2069335-A1 PYRIDIN-3-YL DERIVATIVES AS IMMUNOMODULATING AGENTS Actelion Pharmaceuticals Ltd. (CH) 2009-06-17 EP disclosed
WO-2008114157-A1 AMINO- PYRIDINE DERIVATIVES AS S1P1 /EDG1 RECEPTOR AGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2008-09-25 WO disclosed
WO-2008029371-A1 PYRIDIN-4-YL DERIVATIVES AS IMMUNOMODULATING AGENTS ACTELION PHARMACEUTICALS LTD (CH) 2008-03-13 WO disclosed
WO-2008029371-A1 PYRIDIN-4-YL DERIVATIVES AS IMMUNOMODULATING AGENTS ACTELION PHARMACEUTICALS LTD (CH) 2008-03-13 WO disclosed
WO-2008029370-A1 PYRIDIN-3-YL DERIVATIVES AS IMMUNOMODULATING AGENTS ACTELION PHARMACEUTICALS LTD (CH) 2008-03-13 WO disclosed
WO-2008029370-A1 PYRIDIN-3-YL DERIVATIVES AS IMMUNOMODULATING AGENTS ACTELION PHARMACEUTICALS LTD (CH) 2008-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166638-A1 FUNGICIDAL OXADIAZOLES OXA1L, NOX1, TH CA2 1403/4885CAMK2A 3738/4885AKR1B1 66/4885
US-20100063108-A1 Pyridin-4-yl derivatives as immunomodulating agents CD4, FCGRT, IL2 CA2 4484/4885CAMK2A 3446/4885AKR1B1 630/4885
US-12606548-B2 Fungicidal oxadiazoles AOC2, AOC3, MT-CO3 CA2 306/4885CAMK2A 4219/4885AKR1B1 1718/4885
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH CA2 1403/4885CAMK2A 3738/4885AKR1B1 66/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.