Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.81 |
| ▸ | AR | P10275 | 7/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626100 | 1.00 | PGR (0.81) | PGRNR3C1ARPDE4DCYP3A4 | |
| Nomegestrol Acetate SCHEMBL19760877 | 0.90 | PGR (1.00) | PGRNR3C1ARPDE4DCYP3A4 | |
| Nomegestrol Acetate SCHEMBL37517 | 0.90 | PGR (1.00) | PGRNR3C1ARPDE4DCYP3A4 | |
| Nomegestrol Acetate SCHEMBL8817628 | 0.90 | PGR (1.00) | PGRNR3C1ARPDE4DCYP3A4 | |
| Amadinone Acetate SCHEMBL282893 | 0.87 | NR3C1 (0.81) | PGRNR3C1ARPDE4DCYP3A4 | |
| SCHEMBL20266962 | 0.78 | PGR (0.67) | PGRNR3C1ARPDE4DCYP3A4 | |
| SCHEMBL10952461 | 0.78 | PGR (0.67) | PGRNR3C1ARPDE4DCYP3A4 | |
| Melengestrol Acetate SCHEMBL7759085 | 0.76 | LMNA (0.73) | PGRNR3C1ARPDE4DCYP3A4 | |
| SCHEMBL25334510 | 0.75 | PGR (0.72) | PGRNR3C1ARPDE4DCYP3A4 | |
| SCHEMBL10951986 | 0.75 | PGR (0.72) | PGRNR3C1ARPDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108774279-B | Synthesis method of 6-hydroxymethyl-17 alpha-acetoxyl-19-norpregna-4, 6-diene-3, 20-diketone | 丽江映华生物药业有限公司 | 2021-01-19 | — | — | CN | disclosed |
| CN-108774279-B | Synthesis method of 6-hydroxymethyl-17 alpha-acetoxyl-19-norpregna-4, 6-diene-3, 20-diketone | 丽江映华生物药业有限公司 | 2021-01-19 | — | — | CN | disclosed |