Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP19 | O94966 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | FSHR | P23945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17868357 | 0.77 | GBA1 (0.42) | GBA1ALDH1A1FAAHMGLLGNAO1 | |
| SCHEMBL17868349 | 0.77 | GBA1 (0.42) | GBA1ALDH1A1FAAHMGLLGNAO1 | |
| SCHEMBL25974542 | 0.75 | BRD4 (0.44) | USP19 | |
| SCHEMBL9319727 | 0.75 | GBA1 (0.40) | GBA1ALDH1A1FAAHMGLLGNAO1 | |
| SCHEMBL3491063 | 0.72 | L3MBTL1 (0.43) | ALDH1A1GNAO1L3MBTL1 | |
| SCHEMBL10531648 | 0.72 | GNAI3 (0.42) | ALDH1A1GNAO1BCHEL3MBTL1 | |
| SCHEMBL5234702 | 0.70 | GNAO1 (0.47) | KCNH2GNAO1BCHE | |
| SCHEMBL28499610 | 0.70 | BRD4 (0.54) | GBA1ALDH1A1L3MBTL1 | |
| SCHEMBL9869264 | 0.70 | BRD4 (0.54) | GBA1ALDH1A1L3MBTL1 | |
| SCHEMBL28181325 | 0.70 | GBA1 (0.44) | GBA1ALDH1A1FAAHMGLLGNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-112135818-A | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-112135818-A | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2020-12-25 | — | — | CN | disclosed |