Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496316 | 0.87 | MEN1 (0.42) | IDO1YTHDC1P2RX7MEN1PRNP | |
| SCHEMBL28505004 | 0.85 | SMN1; SMN2 (0.48) | P2RX7MEN1KMT2ATP53MDM4 | |
| SCHEMBL28508709 | 0.83 | HTR1A (0.52) | MEN1KMT2ATP53MDM4MDM2 | |
| SCHEMBL28509176 | 0.83 | MDM4 (0.43) | MEN1KMT2ATP53MDM4MDM2 | |
| SCHEMBL28503167 | 0.81 | TP53 (0.56) | MEN1KMT2ATP53MDM4MDM2 | |
| SCHEMBL28496321 | 0.80 | PRKACA (0.49) | MEN1KMT2ATP53MDM4MDM2 | |
| SCHEMBL28501197 | 0.80 | MDM2 (0.52) | MEN1KMT2ATP53MDM4MDM2 | |
| SCHEMBL28514431 | 0.80 | TP53 (0.52) | MEN1KMT2ATP53MDM4MDM2 | |
| SCHEMBL28492793 | 0.79 | MDM2 (0.62) | MEN1KMT2ATP53MDM4MDM2 | |
| SCHEMBL28507714 | 0.78 | HTR7 (0.48) | MEN1KMT2ATP53MDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174937-B | 3- (5-imidazolyl) indole compound and preparation method and application thereof | 南京农业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112174937-A | 3- (5-imidazolyl) indole compound and preparation method and application thereof | 南京农业大学 | 2021-01-05 | — | — | CN | disclosed |