Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505021 | 0.89 | HTR1A (0.53) | HTR1ADRD2MDM4TP53MDM2 | |
| SCHEMBL28495988 | 0.88 | HTR1A (0.51) | HTR1ADRD2MDM4TP53MDM2 | |
| SCHEMBL28514431 | 0.87 | TP53 (0.52) | HTR1ADRD2MDM4TP53MDM2 | |
| SCHEMBL28492793 | 0.87 | MDM2 (0.62) | DRD2MDM4TP53MDM2MEN1 | |
| SCHEMBL28503167 | 0.87 | TP53 (0.56) | HTR1ADRD2MDM4TP53MDM2 | |
| SCHEMBL28504165 | 0.85 | MDM2 (0.52) | HTR1ADRD2MDM4TP53MDM2 | |
| SCHEMBL28501197 | 0.85 | MDM2 (0.52) | MDM4TP53MDM2MEN1KMT2A | |
| SCHEMBL28503010 | 0.83 | IDO1 (0.43) | HTR1ADRD2MDM4TP53MDM2 | |
| SCHEMBL28505089 | 0.82 | MDM4 (0.49) | HTR1ADRD2MDM4TP53MDM2 | |
| SCHEMBL28496321 | 0.81 | PRKACA (0.49) | MDM4TP53MDM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174937-B | 3- (5-imidazolyl) indole compound and preparation method and application thereof | 南京农业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112174937-A | 3- (5-imidazolyl) indole compound and preparation method and application thereof | 南京农业大学 | 2021-01-05 | — | — | CN | disclosed |