Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 4/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.41 |
| ▸ | ESRRB | O95718 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22394385 | 0.84 | TP53 (0.45) | KCNH2LMNAGPR84ESRRGSLC13A5 | |
| SCHEMBL3079938 | 0.78 | CYP1A2 (0.46) | TRPV1KCNH2GPR84 | |
| SCHEMBL9633727 | 0.78 | NOS3 (0.39) | TRPV1TSHR | |
| SCHEMBL107820 | 0.78 | ESR1 (0.54) | LMNATP53SIGMAR1 | |
| SCHEMBL7456580 | 0.76 | KCNH2 (0.59) | KCNH2LMNAGPR84ESRRGSLC13A5 | |
| SCHEMBL9633317 | 0.76 | ALDH1A1 (0.36) | TRPV1TSHR | |
| SCHEMBL1612731 | 0.76 | KCNH2 (0.47) | KCNH2LMNAGPR84ESRRGSLC13A5 | |
| SCHEMBL1864936 | 0.76 | TP53 (0.52) | KCNH2LMNAGPR84ESRRGSLC13A5 | |
| SCHEMBL66122 | 0.76 | TP53 (0.52) | KCNH2LMNAGPR84ESRRGSLC13A5 | |
| SCHEMBL8955897 | 0.76 | KCNH2 (0.47) | KCNH2LMNAGPR84ESRRGSLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849121-B | Polypeptides having lipase activity and polynucleotides encoding same | 诺维信公司 | 2020-12-29 | — | — | CN | disclosed |