Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615340 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL115452 | 0.71 | RAB9A (0.60) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL3979439 | 0.70 | RAB9A (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL14330030 | 0.67 | GAA (0.59) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5541680 | 0.67 | KDM4E (0.63) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| Benzidine SCHEMBL28824688 | 0.67 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL4390043 | 0.67 | PIK3CG (0.66) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL24037915 | 0.65 | HTR2A (0.40) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL31154078 | 0.65 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL16933414 | 0.65 | NPC1 (0.78) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-A | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2020-12-11 | — | — | CN | disclosed |