Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.60 |
| ▸ | NPC1 | O15118 | 12/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 4/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3979439 | 0.98 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL615340 | 0.84 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL17307530 | 0.83 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL29442076 | 0.79 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9105844 | 0.79 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL13528421 | 0.79 | L3MBTL1 (0.82) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL903255 | 0.79 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL6398262 | 0.79 | MAPT (0.66) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL1192928 | 0.79 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| Iodide SCHEMBL8417295 | 0.78 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-B1 | INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS | UNIV QUEENSLAND (AU) | 2024-07-24 | — | — | EP | claimed |
| US-8461159-B2 | Heteroaryl-substituted urea modulators of fatty acid amide hydrolase | Jannsen Pharmaceutica BV (BE) | 2013-06-11 | — | — | US | claimed |
| WO-2010068453-A1 | HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-06-17 | — | — | WO | claimed |
| US-12528810-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250051325-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2025-02-13 | — | — | US | disclosed |
| CN-119306712-A | Diaryl pyrimidine derivative containing condensed heterocycle and preparation method and application thereof | 山东大学 | 2025-01-14 | — | — | CN | disclosed |
| WO-2024188086-A1 | AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-09-19 | — | — | WO | disclosed |
| US-12054483-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-08-06 | — | — | US | disclosed |
| EP-3246963-B1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO LTD (KR) | 2023-05-31 | — | — | EP | disclosed |
| US-20220153756-A1 | ANTI-INFECTIVE COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2022-05-19 | — | — | US | disclosed |
| US-20220041590-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2022-02-10 | — | — | US | disclosed |
| EP-0294461-B1 | SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1991-10-23 | — | — | EP | disclosed |
| US-5055387-A | Silver halide emulsion layer containing a merocyanine dye on a support | EASTMAN KODAK COMPANY (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0446845-A2 | Sensitizing dye for photographic materials | EASTMAN KODAK COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4940654-A | Solid particle dispersion filter dyes for photographic compositions | EASTMAN KODAK COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4900652-A | FILM SUPPORT CAPABLE OF TRANSMITTING RADIATION. | EASTMAN KODAK COMPANY (US) | 1990-02-13 | — | — | US | disclosed |
| US-4900653-A | SOLUBILITY; CYANINE DYES | EASTMAN KODAK COMPANY (US) | 1990-02-13 | — | — | US | disclosed |
| EP-0323728-A2 | Filter dyes for photographic elements | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-07-12 | — | — | EP | disclosed |
| EP-0294461-A1 | SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS. | EASTMAN KODAK CO (US) | 1988-12-14 | — | — | EP | disclosed |
| WO-1988004794-A1 | SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1988-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528810-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | CLK3, CLK2, CLK1 | RAB9A 3245/4885NPC1 3157/4885SMN1; SMN2 3372/4885 |
| US-20220153756-A1 | ANTI-INFECTIVE COMPOUNDS | RABGGTB, ELANE, SERPINB1 | RAB9A 1091/4885NPC1 402/4885SMN1; SMN2 4839/4885 |
| US-20220041590-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | CLK2, CLK1, CLK3 | RAB9A 4181/4885NPC1 3961/4885SMN1; SMN2 4476/4885 |
| US-12054483-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | CLK2, CLK1, CLK3 | RAB9A 4181/4885NPC1 3961/4885SMN1; SMN2 4476/4885 |
| US-20250051325-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | CLK2, CLK1, CLK3 | RAB9A 4181/4885NPC1 3961/4885SMN1; SMN2 4476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.