Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.42 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.42 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856000 | 0.78 | CCR1 (0.55) | HPGDALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL2850622 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTPOLB | |
| SCHEMBL2852975 | 0.74 | CCR1 (0.55) | HPGDALDH1A1MAPTPOLBNR3C1 | |
| SCHEMBL2853245 | 0.73 | ALDH1A1 (0.68) | HPGDALDH1A1MAPTPOLB | |
| SCHEMBL6357279 | 0.73 | HPGD (0.63) | EZH2HPGDTP53GLAALDH1A1 | |
| SCHEMBL2855548 | 0.72 | CCR1 (0.68) | HPGDKMT2A | |
| SCHEMBL23083259 | 0.72 | SMN1; SMN2 (0.62) | HPGDTP53GLAALDH1A1MAPT | |
| SCHEMBL2852998 | 0.70 | NPC1 (0.59) | HPGDGLAALDH1A1MAPTKMT2A | |
| SCHEMBL5723907 | 0.70 | MTNR1A (0.56) | ALDH1A1ROCK2 | |
| SCHEMBL9204354 | 0.70 | CYP1A2 (0.44) | HPGDGLAALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |