Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3520114 | 0.92 | SMN1; SMN2 (0.58) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL4456501 | 0.82 | HIF1A (0.53) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4456375 | 0.77 | P2RX7 (0.55) | ALDH1A1HPGDKMT2ALMNAP2RX7 | |
| SCHEMBL2857896 | 0.76 | HPGD (0.77) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL22640054 | 0.75 | NPC1 (0.56) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL6356707 | 0.75 | NPC1 (1.00) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2854054 | 0.74 | MAPT (0.57) | ALDH1A1LMNAMAPTNR3C1CCNA2 | |
| SCHEMBL2853014 | 0.74 | KDM4E (0.60) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28218732 | 0.74 | RAB9A (0.57) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL2852043 | 0.74 | KDM4E (0.70) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |