Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853232 | 0.90 | CCR1 (0.48) | KMT2AMEN1NPC1MAPK1DHODH | |
| SCHEMBL2880130 | 0.89 | MAPK1 (0.54) | NAMPTABCB1NPC1MAPK1RAB9A | |
| SCHEMBL2854455 | 0.83 | KMT2A (0.50) | KMT2AMEN1ABCB1MAPK1DHODH | |
| SCHEMBL2856146 | 0.82 | CNR1 (0.53) | KMT2AMEN1ABCB1NPC1MAPK1 | |
| SCHEMBL2859025 | 0.82 | NAMPT (0.44) | KMT2ANAMPTMEN1ABCB1NPC1 | |
| SCHEMBL2858063 | 0.82 | MAPT (0.57) | NPC1RAB9A | |
| SCHEMBL2854852 | 0.82 | ABCB1 (0.49) | KMT2ANAMPTMEN1ABCB1DHODH | |
| SCHEMBL2880891 | 0.81 | CNR1 (0.54) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2857827 | 0.80 | MEN1 (0.55) | KMT2AMEN1NPC1MAPK1RAB9A | |
| SCHEMBL2854457 | 0.80 | CYP3A4 (0.43) | KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |