Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853193 | 0.91 | MAPT (0.43) | ABCB1KMT2ADHODHMCHR1CCR1 | |
| SCHEMBL2853388 | 0.90 | CCR1 (0.48) | ABCB1KMT2ADHODHCCR1SMN1; SMN2 | |
| SCHEMBL2854322 | 0.89 | ABCB1 (0.45) | ABCB1CCR1SMN1; SMN2NAMPTKDM4E | |
| SCHEMBL2860435 | 0.89 | NAMPT (0.46) | KMT2ADHODHEPHX1NAMPTGAA | |
| SCHEMBL2856356 | 0.86 | ALDH1A1 (0.47) | ABCB1KMT2ACCR1HTTSMN1; SMN2 | |
| SCHEMBL2849956 | 0.86 | CCR1 (0.62) | KMT2ACCR1LMNAGAAMEN1 | |
| SCHEMBL2855714 | 0.85 | EPHX1 (0.45) | KMT2AHTTEPHX1NAMPTMEN1 | |
| SCHEMBL2853334 | 0.85 | CCR1 (0.47) | CCR1ALDH1A1 | |
| SCHEMBL2850425 | 0.85 | P2RX7 (0.49) | CCR1 | |
| SCHEMBL2852635 | 0.85 | EPHX1 (0.44) | KMT2AMCHR1EPHX1NAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |