Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854824 | 0.91 | POLB (0.44) | HPGDKDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL2848617 | 0.83 | NPC1 (0.47) | HPGDKDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL2858207 | 0.82 | HSD17B10 (0.52) | HPGDKDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL2855394 | 0.81 | ALDH1A1 (0.54) | POLBLMNARAB9AALDH1A1MAPK1 | |
| SCHEMBL2856416 | 0.79 | ALDH1A1 (0.52) | POLBLMNARAB9AALDH1A1MAPK1 | |
| SCHEMBL2863421 | 0.79 | EPHX1 (0.46) | HPGDPOLBLMNARAB9AALDH1A1 | |
| SCHEMBL2852393 | 0.79 | ALDH1A1 (0.43) | HPGDPOLBLMNARAB9AALDH1A1 | |
| SCHEMBL2856997 | 0.79 | ALDH1A1 (0.57) | POLBLMNARAB9AALDH1A1MAPK1 | |
| SCHEMBL5325459 | 0.78 | ALDH1A1 (0.53) | POLBLMNARAB9AALDH1A1MAPK1 | |
| SCHEMBL2855497 | 0.78 | MAPT (0.52) | POLBLMNARAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |