Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850503 | 0.82 | HPGD (0.48) | HSD17B10ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL2855394 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNARAB9ATP53MAPT | |
| SCHEMBL2856416 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNARAB9AMAPTMAPK1 | |
| SCHEMBL2863421 | 0.79 | EPHX1 (0.46) | ALDH1A1LMNARAB9AMAPTMAPK1 | |
| SCHEMBL2852393 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNARAB9AMAPTMAPK1 | |
| SCHEMBL2856997 | 0.79 | ALDH1A1 (0.57) | ALDH1A1LMNARAB9AMAPTMAPK1 | |
| SCHEMBL5325459 | 0.78 | ALDH1A1 (0.53) | ALDH1A1LMNARAB9AMAPTMAPK1 | |
| SCHEMBL2855497 | 0.78 | MAPT (0.52) | ALDH1A1LMNARAB9AMAPTMAPK1 | |
| SCHEMBL2852403 | 0.78 | CACNA1G (0.43) | ALDH1A1LMNARAB9AMAPTMAPK1 | |
| SCHEMBL2857176 | 0.78 | ALDH1A1 (0.46) | ALDH1A1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |