Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848617 | 0.92 | NPC1 (0.47) | POLBALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2850503 | 0.91 | HPGD (0.48) | POLBKMT2AALDH1A1MAPK1MAPT | |
| SCHEMBL2856936 | 0.82 | KDM4E (0.45) | POLBKMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL2853163 | 0.82 | ALDH1A1 (0.45) | POLBALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2861640 | 0.82 | ALDH1A1 (0.45) | POLBALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2856513 | 0.81 | TAAR1 (0.51) | KMT2AALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2852521 | 0.81 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2860235 | 0.81 | LMNA (0.47) | POLBALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2856225 | 0.81 | ALDH1A1 (0.44) | POLBALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2857176 | 0.81 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPK1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |