Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853456 | 0.85 | KMT2A (0.46) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL2860822 | 0.82 | MAPT (0.45) | MAPT | |
| SCHEMBL2859374 | 0.82 | MAPT (0.52) | NPSR1SMN1; SMN2MAPTATM | |
| SCHEMBL2855798 | 0.81 | MAPT (0.45) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL2854721 | 0.79 | MAPT (0.42) | MEN1KMT2APOLBSMN1; SMN2RAB9A | |
| SCHEMBL2860500 | 0.76 | TP53 (0.54) | MEN1KMT2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL2859029 | 0.75 | FFAR2 (0.46) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL2850712 | 0.75 | MAPT (0.41) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL2850385 | 0.75 | CA2 (0.50) | MEN1KMT2AMAPT | |
| SCHEMBL2852244 | 0.74 | MAPT (0.48) | MEN1KMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |