Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859374 | 0.87 | MAPT (0.52) | MAPTCCR1CA1CA2CA4 | |
| SCHEMBL2857550 | 0.86 | TMPRSS4 (0.45) | MAPTCCR1ACHE | |
| SCHEMBL2855798 | 0.85 | MAPT (0.45) | MAPTCCR1CA1CA2CA4 | |
| SCHEMBL2848541 | 0.84 | RAB9A (0.43) | MAPTCCR1MAPK14ACHE | |
| SCHEMBL2859712 | 0.84 | CA1 (0.45) | MAPTCA1CA2CA4CA9 | |
| SCHEMBL2850806 | 0.82 | MAPT (0.47) | MAPTMAPK14 | |
| SCHEMBL2850752 | 0.82 | MEN1 (0.54) | MAPT | |
| SCHEMBL2858182 | 0.82 | P2RX7 (0.44) | MAPT | |
| SCHEMBL2853182 | 0.82 | MAPT (0.42) | MAPTCCR1ACHE | |
| SCHEMBL2850809 | 0.81 | MAPT (0.43) | MAPTCCR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |