Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20319189 | 0.83 | HPGD (0.50) | L3MBTL1TDP1CYP1A2SLC6A2SLC6A3 | |
| SCHEMBL45228 | 0.82 | LMNA (0.50) | L3MBTL1TDP1LMNAPTGS1CYP2C19 | |
| SCHEMBL3423751 | 0.82 | TDP1 (0.74) | L3MBTL1TDP1LMNABCHEGAA | |
| Ammonia Solution, Strong SCHEMBL27757668 | 0.80 | LMNA (0.49) | L3MBTL1TDP1LMNAPTGS1CYP2C19 | |
| Methane SCHEMBL11161392 | 0.80 | LMNA (0.49) | L3MBTL1TDP1LMNAPTGS1CYP2C19 | |
| SCHEMBL9825918 | 0.80 | LMNA (0.49) | L3MBTL1TDP1LMNAPTGS1CYP2C19 | |
| SCHEMBL10599543 | 0.80 | LMNA (0.69) | L3MBTL1MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL11856925 | 0.80 | LMNA (0.69) | L3MBTL1MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL28547424 | 0.78 | CALM1 (0.50) | L3MBTL1TDP1LMNAPTGS1CYP2C19 | |
| Methyl Alcohol SCHEMBL5311361 | 0.77 | LMNA (0.50) | L3MBTL1TDP1LMNAPTGS1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112190571-B | Application of gastrodia tuber source derivative in preparing medicine for treating inflammatory bowel disease | 中国医学科学院药物研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-112190570-B | Application of gastrodia tuber source derivative in preparing medicine for treating acute or chronic pain | 中国医学科学院药物研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-112190571-A | Application of derivative from gastrodia elata in preparation of medicine for treating inflammatory bowel disease | 中国医学科学院药物研究所 | 2021-01-08 | — | — | CN | disclosed |
| CN-112190570-A | Application of derivative derived from rhizoma gastrodiae in preparation of medicine for treating acute or chronic pain | 中国医学科学院药物研究所 | 2021-01-08 | — | — | CN | disclosed |