Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28903711 | 0.89 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EALDH1A1KMT2AHTR2A | |
| SCHEMBL28903731 | 0.85 | CA1 (0.43) | SMN1; SMN2LMNAKDM4EPOLBCA1 | |
| SCHEMBL28489446 | 0.85 | LSS (0.41) | SMN1; SMN2LMNACYP19A1ALDH1A1PDE4B | |
| SCHEMBL28489906 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2LMNAKDM4EPOLBHTT | |
| SCHEMBL28497515 | 0.80 | LMNA (0.48) | SMN1; SMN2LMNAKDM4EPOLBHTT | |
| SCHEMBL28497451 | 0.80 | MTNR1A (0.40) | KDM4EPOLBCA1CA2ALDH1A1 | |
| SCHEMBL28496766 | 0.74 | MTNR1A (0.43) | POLB | |
| SCHEMBL28509136 | 0.73 | ALDH1A1 (0.56) | SMN1; SMN2LMNAKDM4EPOLBHTT | |
| SCHEMBL28498473 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EPOLBALDH1A1KMT2A | |
| SCHEMBL28498699 | 0.69 | POLB (0.46) | SMN1; SMN2POLBHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110932-B | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112110932-A | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |