Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | AXL | P30530 | 4/20 | 0.37 |
| ▸ | MERTK | Q12866 | 3/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28574601 | 0.99 | LOXL2 (0.39) | LOXL2AXLMERTKNTRK1SYK | |
| SCHEMBL18072475 | 0.85 | LOXL2 (0.55) | LOXL2AXLMERTKSYKKDM4E | |
| SCHEMBL18049928 | 0.85 | LOXL2 (0.55) | LOXL2 | |
| Hydrochloric Acid SCHEMBL18050037 | 0.84 | LOXL2 (0.55) | LOXL2 | |
| SCHEMBL19739420 | 0.82 | LOXL2 (0.37) | LOXL2AXLMERTKSYKMAP4K1 | |
| SCHEMBL28510258 | 0.82 | TYRO3 (0.36) | LOXL2AXLMERTKSYKTYRO3 | |
| SCHEMBL19755757 | 0.73 | LOXL2 (0.40) | LOXL2SYKNPSR1MAP4K1HTR3A | |
| SCHEMBL19755754 | 0.73 | LOXL2 (0.41) | LOXL2SYKMAP4K1HTR3AIRAK4 | |
| SCHEMBL28906716 | 0.72 | LOXL2 (0.35) | LOXL2SYKTYRO3MAP4K1HTR3A | |
| SCHEMBL18361992 | 0.70 | LOXL2 (0.38) | LOXL2SYKTYRO3MAP4K1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107592861-B | Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof | 法玛克亚公司 | 2021-06-08 | — | — | CN | disclosed |