Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.62 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.53 |
| ▸ | FEN1 | P39748 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136810 | 0.87 | MET (0.55) | METALOX5APFEN1NOS3NOS1 | |
| SCHEMBL29631575 | 0.87 | MET (0.55) | METALOX5APFEN1NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL1137241 | 0.86 | MET (0.54) | METALOX5APFEN1NOS3NOS1 | |
| SCHEMBL797972 | 0.82 | MET (0.54) | METALOX5APFEN1NOS3NOS1 | |
| SCHEMBL28518598 | 0.81 | TRPA1 (0.48) | METTRPA1 | |
| SCHEMBL14742548 | 0.81 | MET (0.49) | METALOX5APFEN1NOS3NOS1 | |
| SCHEMBL30844467 | 0.79 | HSPB1 (0.53) | METALOX5APFEN1 | |
| SCHEMBL197935 | 0.79 | HSPB1 (0.53) | METALOX5APFEN1 | |
| SCHEMBL5124463 | 0.78 | MET (0.56) | METALOX5APFEN1NOS3NOS1 | |
| SCHEMBL4338310 | 0.78 | MET (1.00) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300154-B | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112300154-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-02-02 | — | — | CN | disclosed |