Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29487171 | 0.84 | MET (0.42) | METGCK | |
| SCHEMBL1136992 | 0.84 | MET (0.42) | METGCK | |
| SCHEMBL15832082 | 0.83 | TRPA1 (0.50) | TRPA1GCK | |
| SCHEMBL29918375 | 0.81 | RECQL (0.53) | MET | |
| SCHEMBL14656193 | 0.81 | RECQL (0.53) | MET | |
| SCHEMBL24999541 | 0.81 | MAPK14 (0.42) | TRPA1GCK | |
| SCHEMBL14656150 | 0.81 | ALDH1A1 (0.43) | METGCK | |
| SCHEMBL28510567 | 0.81 | MET (0.62) | TRPA1MET | |
| SCHEMBL1415532 | 0.80 | S1PR2 (0.46) | TRPA1HSPB1GRM5 | |
| SCHEMBL15500642 | 0.79 | GCK (0.36) | TRPA1METGRM5GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300154-B | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112300154-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-02-02 | — | — | CN | disclosed |