Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30555191 | 1.00 | POLB (0.51) | POLBKMT2AMEN1NPSR1USP2 | |
| SCHEMBL30074470 | 0.90 | POLB (0.58) | POLBKMT2AMEN1NPSR1GAA | |
| SCHEMBL8238318 | 0.82 | KIF11 (0.51) | POLBRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13368505 | 0.82 | NPC1 (0.51) | POLBKMT2AMEN1NPSR1GAA | |
| SCHEMBL30555190 | 0.79 | CYP1A2 (0.46) | POLBKMT2AMEN1NPSR1GAA | |
| SCHEMBL20003938 | 0.79 | POLB (0.45) | POLBKMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL20003906 | 0.78 | KDR (0.56) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6715811 | 0.77 | RAB9A (0.52) | POLBKMT2AMEN1NPSR1USP2 | |
| SCHEMBL2056400 | 0.76 | SPHK1 (0.53) | POLBKMT2ANPSR1RAB9ANPC1 | |
| SCHEMBL6918008 | 0.76 | POLB (0.66) | POLBKMT2AMEN1USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142619-B | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112142619-A | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2020-12-29 | — | — | CN | disclosed |