Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14638146 | 0.88 | POLB (0.65) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL14637558 | 0.88 | LMNA (0.68) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL18730260 | 0.85 | POLB (0.68) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL6202951 | 0.82 | LMNA (0.68) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL24340171 | 0.81 | POLB (0.63) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL5947301 | 0.81 | DRD2 (0.61) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL9227281 | 0.80 | KCNH2 (0.64) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL7247553 | 0.80 | POLB (0.61) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL11103861 | 0.80 | POLB (0.73) | LMNASMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL8103874 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2TSHRPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226807-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |