Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499649 | 0.90 | SMN1; SMN2 (0.69) | LMNASMN1; SMN2ALDH1A1HSD11B1KMT2A | |
| Hydrochloric Acid SCHEMBL9502312 | 0.88 | SMN1; SMN2 (0.67) | LMNASMN1; SMN2ALDH1A1HSD11B1KMT2A | |
| SCHEMBL9500292 | 0.85 | ALDH1A1 (0.69) | LMNASMN1; SMN2ALDH1A1HSD11B1KMT2A | |
| Hydrochloric Acid SCHEMBL9501099 | 0.84 | LMNA (0.68) | LMNASMN1; SMN2HSD11B1KMT2ACYP1A2 | |
| SCHEMBL14637558 | 0.83 | LMNA (0.68) | LMNASMN1; SMN2ALDH1A1HSD11B1KMT2A | |
| SCHEMBL28512371 | 0.82 | LMNA (0.70) | LMNASMN1; SMN2ALDH1A1HSD11B1KMT2A | |
| SCHEMBL6201613 | 0.81 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2ALDH1A1HSD11B1CYP2C19 | |
| SCHEMBL10726829 | 0.81 | HSD11B1 (0.63) | LMNASMN1; SMN2ALDH1A1HSD11B1KMT2A | |
| SCHEMBL6210639 | 0.81 | HSD11B1 (1.00) | LMNASMN1; SMN2ALDH1A1HSD11B1CYP2C19 | |
| Hydrochloric Acid SCHEMBL9341757 | 0.81 | MEN1 (0.54) | LMNASMN1; SMN2ALDH1A1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |