Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.47 |
| ▸ | LDHB | P07195 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13452821 | 0.86 | PPARG (0.48) | GRM2PPARALMNACYP1A2MAPT | |
| SCHEMBL2581660 | 0.85 | KDM4E (0.50) | LDHAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8262764 | 0.84 | HSP90AB1 (0.43) | LDHALDHBKDM4EHSD17B10GRM2 | |
| SCHEMBL10726758 | 0.84 | SELL (0.53) | LDHALDHBKDM4EALDH1A1HPGD | |
| SCHEMBL8226800 | 0.84 | GABRP (0.41) | LDHALDHBKDM4EALDH1A1HPGD | |
| SCHEMBL28732290 | 0.82 | PPARA (0.41) | LDHALDHBKDM4EPPARAMCL1 | |
| SCHEMBL8321013 | 0.81 | CTSD (0.41) | LDHALDHBHSD17B10GRM2PPARA | |
| SCHEMBL2924329 | 0.81 | MMP2 (0.46) | LDHALDHBKDM4EALDH1A1SELL | |
| SCHEMBL6693155 | 0.80 | PPARA (0.49) | KDM4EALDH1A1HPGDHSD17B10SELL | |
| SCHEMBL750714 | 0.78 | CYP1A2 (0.46) | LDHALDHBKDM4EPPARAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573036-B | Combination therapy for ameliorating adverse side effects of chemotherapy | 益生生技开发股份有限公司 | 2021-02-02 | — | — | CN | disclosed |