Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534296 | 0.90 | GHSR (0.49) | GAANOTUMSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL30047263 | 0.80 | ALDH1A1 (0.52) | GAATSHR | |
| SCHEMBL259951 | 0.80 | ALDH1A1 (0.52) | GAATSHR | |
| SCHEMBL14022821 | 0.77 | MTNR1A (0.47) | TSHRMTNR1AMTNR1B | |
| SCHEMBL24045426 | 0.77 | ALDH1A1 (0.46) | GAATSHRSMN1; SMN2LMNA | |
| SCHEMBL2246761 | 0.77 | GAA (0.47) | GAANOTUMTSHR | |
| SCHEMBL7334700 | 0.76 | MTNR1A (0.47) | GAANAMPTSMN1; SMN2PPIDMTNR1A | |
| SCHEMBL15785717 | 0.76 | AKR1C3 (0.46) | TSHRSMN1; SMN2 | |
| SCHEMBL12611599 | 0.76 | AKR1C3 (0.46) | TSHRSMN1; SMN2 | |
| SCHEMBL7909264 | 0.75 | ATM (0.52) | GAANFKB1NFKB2RELASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358482-A | [1,2,4] triazole derivative and application thereof in preparation of medicines for treating neurodegenerative diseases and premature ovarian failure | 李奇峰 | 2021-02-12 | — | — | CN | claimed |
| CN-112358482-A | [1,2,4] triazole derivative and application thereof in preparation of medicines for treating neurodegenerative diseases and premature ovarian failure | 李奇峰 | 2021-02-12 | — | — | CN | disclosed |