Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PARL | Q9H300 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23581205 | 0.82 | MMP2 (0.46) | CA12MMP2CA9GAAALDH1A1 | |
| SCHEMBL140930 | 0.81 | MMP2 (0.47) | CA12MMP2CA9CA14GAA | |
| SCHEMBL3149080 | 0.81 | CA2 (0.47) | CA12MMP2CA9CA14GAA | |
| Pyridine SCHEMBL156519 | 0.78 | STAT3 (0.40) | CA12MMP2CA9CA14GAA | |
| SCHEMBL27714770 | 0.78 | PIN1 (0.44) | CA12MMP2CA9CA14PARL | |
| Butane SCHEMBL15941687 | 0.78 | MMP2 (0.44) | CA12MMP2CA9CA14GAA | |
| SCHEMBL8583278 | 0.77 | TDP1 (0.47) | CA12MMP2CA9CA14GAA | |
| SCHEMBL385110 | 0.76 | KMT2A (0.52) | MMP2CA9GAACYP2C9CYP2C19 | |
| SCHEMBL13488465 | 0.75 | PARL (0.47) | CA12MMP2CA9CA14PARL | |
| SCHEMBL29774731 | 0.75 | PARL (0.47) | CA12MMP2CA9CA14PARL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409706-A | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2022-04-29 | — | — | CN | claimed |
| CN-112175003-B | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2022-02-15 | — | — | CN | claimed |
| CN-112175003-A | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2021-01-05 | — | — | CN | claimed |
| CN-114409706-A | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2022-04-29 | — | — | CN | disclosed |
| CN-112175003-B | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2022-02-15 | — | — | CN | disclosed |
| CN-112175003-A | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2021-01-05 | — | — | CN | disclosed |
| CN-106632482-A | mPEG3-tenofovir disoproxil and preparation method thereof | 天津迈德新医药科技有限公司 | 2017-05-10 | — | — | CN | disclosed |