Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897342 | 0.79 | QDPR (0.54) | QDPR | |
| SCHEMBL18620920 | 0.76 | QDPR (0.47) | QDPR | |
| SCHEMBL4154520 | 0.75 | QDPR (0.40) | QDPR | |
| SCHEMBL24269979 | 0.75 | MAPK1 (0.53) | — | |
| SCHEMBL24722865 | 0.75 | P2RX7 (0.32) | — | |
| SCHEMBL28503673 | 0.75 | HTR6 (0.56) | HTR6QDPRSLC6A4 | |
| SCHEMBL24802975 | 0.74 | SLC6A4 (0.41) | QDPRSLC6A4 | |
| SCHEMBL24723471 | 0.74 | P2RX7 (0.33) | — | |
| SCHEMBL15581068 | 0.74 | LPL (0.44) | — | |
| SCHEMBL31536273 | 0.73 | QDPR (0.45) | HTR6QDPRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116848113-A | Bicyclic compounds as HPK1 inhibitors and application thereof | 南京再明医药有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-112243439-A | Pyrrolo [2,3-B ] pyridines or pyrrolo [2,3-B ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-01-19 | — | — | CN | disclosed |