Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434547 | 0.84 | MAPT (0.65) | MAPTKMT2AMEN1CYP19A1LNPEP | |
| SCHEMBL30737524 | 0.84 | HTR6 (0.79) | HTR6POLBKMT2AMEN1CYP19A1 | |
| SCHEMBL28271815 | 0.84 | HTR6 (0.79) | HTR6POLBKMT2AMEN1CYP19A1 | |
| SCHEMBL28271796 | 0.84 | HTR6 (0.83) | HTR6POLBKMT2ACYP19A1LMNA | |
| SCHEMBL30737484 | 0.83 | PGR (0.71) | HTR6POLBMAPTKMT2AMEN1 | |
| SCHEMBL16431575 | 0.83 | PGR (0.71) | HTR6POLBMAPTKMT2AMEN1 | |
| SCHEMBL25373350 | 0.83 | MAPT (0.62) | HTR6MAPTKMT2AMEN1LMNA | |
| SCHEMBL28271812 | 0.82 | HTR6 (1.00) | HTR6POLBKMT2ACYP19A1PKM | |
| SCHEMBL7579053 | 0.82 | PGR (0.75) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10361762 | 0.82 | MAPT (0.65) | MAPTKMT2AMEN1LNPEPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081793-B | Sulfonamide urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109096156-B | Disulfonyl meta-aryl diamine urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-01-15 | — | — | CN | disclosed |