Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.79 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.78 |
| ▸ | CDC25A | P30304 | 1/20 | 0.66 |
| ▸ | CDC25B | P30305 | 1/20 | 0.66 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CCR2 | P41597 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737524 | 1.00 | HTR6 (0.79) | HTR6CYP19A1CDC25ACDC25BCES1 | |
| SCHEMBL28271812 | 0.88 | HTR6 (1.00) | HTR6CYP19A1POLBCA1CA2 | |
| SCHEMBL28539211 | 0.87 | HTR6 (0.69) | HTR6CYP19A1CDC25ACDC25BPOLB | |
| SCHEMBL16431575 | 0.86 | PGR (0.71) | HTR6CYP19A1POLBKMT2AMEN1 | |
| SCHEMBL30737484 | 0.86 | PGR (0.71) | HTR6CYP19A1POLBKMT2AMEN1 | |
| SCHEMBL2723618 | 0.85 | HTR6 (1.00) | HTR6POLBCA1CA2FFAR4 | |
| SCHEMBL28513724 | 0.84 | HTR6 (0.69) | HTR6CYP19A1CDC25ACDC25BPOLB | |
| SCHEMBL9763115 | 0.84 | HTR6 (0.79) | HTR6CYP19A1POLBCA1CA2 | |
| SCHEMBL3088575 | 0.84 | HTR6 (0.79) | HTR6CYP19A1POLBCA1CA2 | |
| SCHEMBL30737507 | 0.84 | HTR6 (0.79) | HTR6CYP19A1POLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081793-B | Sulfonamide urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109081793-A | Sulfonamides urease inhibitor and its preparation method and purposes | 吉首大学 | 2018-12-25 | — | — | CN | disclosed |