Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | F7 | P08709 | 3/20 | 0.52 |
| ▸ | F3 | P13726 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285137 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL607734 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL22553035 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL22553034 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL1551181 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL10716057 | 0.98 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL10716055 | 0.98 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL1477259 | 0.93 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL15057585 | 0.93 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL605503 | 0.93 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390378-B1 | PHARMACEUTICALLY ACTIVE URIDINE ESTERS | TROMMSDORFF ARZNEIMITTEL (DE) | 2009-06-17 | — | — | EP | claimed |
| US-7396826-B2 | Pharmaceutically active uridine esters | TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2008-07-08 | — | — | US | claimed |
| US-20040121979-A1 | Pharmaceutically active uridine esters | TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2004-06-24 | — | — | US | claimed |
| WO-2023211930-A1 | DUAL FUNCTIONING IMMUNE MODULATING COMPOUNDS, FORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023211934-A1 | LIPIDS, FORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023211940-A1 | STING AGONISTS, FORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20230293629-A1 | METHODS FOR ATTENUATING RELEASE OF INFLAMMATORY MEDIATORS AND PEPTIDES USEFUL THEREIN | BIOMARCK PHARMACEUTICALS LTD (US) | 2023-09-21 | — | — | US | disclosed |
| US-20220305078-A1 | PEPTIDES AND METHODS OF USE THEREOF IN TREATING UVEITIS | PARK STRATEGIC VENTURES LLC | 2022-09-29 | — | — | US | disclosed |
| EP-3982928-A1 | PEPTIDES AND METHODS OF USE THEREOF IN TREATING UVEITIS | Biomarck Pharmaceuticals, Ltd. (US) | 2022-04-20 | — | — | EP | disclosed |
| CN-114302706-A | Peptides for treating uveitis and methods of use thereof | 碧奥马尔克制药有限公司 | 2022-04-08 | — | — | CN | disclosed |
| WO-2020257162-A1 | PEPTIDES AND METHODS OF USE THEREOF IN TREATING UVEITIS | BIOMARCK PHARMACEUTICALS LTD. (US) | 2020-12-24 | — | — | WO | disclosed |
| US-20050043269-A1 | Pharmaceutically active uridine esters | TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL | 2005-02-24 | — | — | US | disclosed |
| US-20050043394-A1 | Pharmaceutically active uridine esters | TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL | 2005-02-24 | — | — | US | disclosed |
| US-20040121979-A1 | Pharmaceutically active uridine esters | TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2004-06-24 | — | — | US | disclosed |
| US-6589977-B1 | Bisindolylpyrrole derivatives represented by general formula (I) which are useful in inhibiting cell death and expected as being useful as preventives and remedies for the progress of various diseases in the progress and worsening of which cell | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-07-08 | — | — | US | disclosed |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-05-08 | — | — | US | disclosed |
| EP-1275646-A1 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-1224932-A1 | DRUGS INHIBITING CELL DEATH | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2002-07-24 | — | — | EP | disclosed |
| EP-1152002-A1 | PYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2001-11-07 | — | — | EP | disclosed |
| EP-1057484-A1 | CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043394-A1 | Pharmaceutically active uridine esters | UMPS, UGDH, FFAR3 | ALDH1A1 342/4885CYP19A1 1191/4885F7 1255/4885 |
| US-20040121979-A1 | Pharmaceutically active uridine esters | UMPS, UGDH, FFAR1 | ALDH1A1 142/4885CYP19A1 958/4885F7 1183/4885 |
| US-20050043269-A1 | Pharmaceutically active uridine esters | UMPS, UGDH, FFAR3 | ALDH1A1 342/4885CYP19A1 1191/4885F7 1255/4885 |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | AIFM1, BAX, CASP3 | ALDH1A1 1068/4885CYP19A1 3515/4885F7 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.