Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372387 | 0.89 | TSHR (0.54) | GLATSHRHTR2CALDH1A1BACE1 | |
| SCHEMBL7412066 | 0.86 | TSHR (0.48) | GLATSHRHTR2CALDH1A1BACE1 | |
| SCHEMBL4758450 | 0.83 | TSHR (0.51) | GLATSHRHTR2CALDH1A1 | |
| SCHEMBL489770 | 0.83 | TSHR (0.51) | GLATSHRHTR2CALDH1A1 | |
| SCHEMBL3447413 | 0.83 | TSHR (0.51) | GLATSHRHTR2CALDH1A1 | |
| SCHEMBL434313 | 0.79 | HTR2C (0.52) | TSHRHTR2CALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8602762 | 0.79 | ALDH1A1 (0.43) | GLATSHRHTR2CALDH1A1BACE1 | |
| SCHEMBL8604142 | 0.79 | ALDH1A1 (0.43) | GLATSHRHTR2CALDH1A1BACE1 | |
| SCHEMBL18545121 | 0.78 | SMN1; SMN2 (0.51) | GLATSHRHTR2CKMT2A | |
| SCHEMBL6167045 | 0.78 | CTSC (0.46) | GLATSHRHTR2CALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368289-B | C26-linked rapamycin analogues as MTOR inhibitors | 锐新医药公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-115916194-A | Methods for delaying, preventing and treating acquired resistance to RAS inhibitors | 锐新医药公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-112771054-A | C40-, C28-and C-32-linked rapamycin analogs as mTOR inhibitors | 锐新医药公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112368289-A | C26-linked rapamycin analogs as MTOR inhibitors | 锐新医药公司 | 2021-02-12 | — | — | CN | disclosed |