Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28134701 | 0.90 | LMNA (0.45) | LMNACA2CA1CA9MEN1 | |
| SCHEMBL28743859 | 0.83 | PPARG (0.47) | LMNACA2CA1CA9MEN1 | |
| SCHEMBL8339186 | 0.76 | LMNA (0.36) | LMNACA2CA1CA9MEN1 | |
| SCHEMBL31469867 | 0.76 | LMNA (0.47) | LMNACA2CA1CA9MEN1 | |
| SCHEMBL6891702 | 0.74 | ALDH1A1 (0.35) | LMNACA2CA1CA9KMT2A | |
| SCHEMBL27585872 | 0.72 | CA1 (0.47) | CA2CA1CA9MEN1KMT2A | |
| SCHEMBL24278496 | 0.72 | ALDH1A1 (0.39) | CA2CA1CA9MEN1KMT2A | |
| SCHEMBL31717331 | 0.72 | TRPV4 (0.39) | LMNACA2CA1CA9KMT2A | |
| SCHEMBL3100955 | 0.71 | MEN1 (0.53) | LMNACA2CA1CA9MEN1 | |
| SCHEMBL8057975 | 0.71 | MEN1 (0.53) | LMNACA2CA1CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916836-B | Method for producing 2-fluoro-4-borono-L-phenylalanine and precursor thereof | 斯特拉制药公司 | 2021-02-09 | — | — | CN | disclosed |