Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891702 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MAPTPOLBHPGDALOX12 | |
| SCHEMBL2426442 | 0.80 | TRPV4 (0.42) | TRPV4L3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL29627448 | 0.80 | TRPV4 (0.42) | TRPV4L3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL24278496 | 0.79 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL692131 | 0.78 | ALDH1A1 (0.47) | TRPV4L3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL3775195 | 0.78 | TRPV4 (0.37) | TRPV4ALDH1A1CA1CA2CA9 | |
| SCHEMBL29907222 | 0.77 | TRPV4 (0.53) | TRPV4ALDH1A1KMT2AGAACA1 | |
| SCHEMBL1200665 | 0.77 | TRPV4 (0.53) | TRPV4ALDH1A1KMT2AGAACA1 | |
| SCHEMBL2748706 | 0.76 | CA1 (0.40) | TRPV4L3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL31066292 | 0.75 | CCR2 (0.37) | TRPV4CA1CA2CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025224168-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-30 | — | — | WO | disclosed |