Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28506838 | 0.90 | RAB9A (0.52) | PTPN11TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1105504 | 0.81 | TSHR (0.67) | PTPN11TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29374341 | 0.81 | ALDH1A1 (0.55) | PTPN11TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28516020 | 0.81 | PTPN11 (0.51) | PTPN11TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29985379 | 0.81 | MAPT (0.54) | PTPN11TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24230149 | 0.81 | ALDH1A1 (0.55) | PTPN11TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28524741 | 0.81 | PTPN11 (0.51) | PTPN11TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22116791 | 0.81 | MAPT (0.54) | PTPN11TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL69268 | 0.80 | PTPN11 (0.69) | PTPN11TSHRMAPTALDH1A1KDM4E | |
| SCHEMBL28520313 | 0.76 | APP (0.50) | KMT2AMEN1RAB9AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110656346-B | Method for continuously preparing 2-aryl-3-halogenated-benzothiophene compound by using electrochemical microchannel reaction device | 南京工业大学 | 2021-02-02 | — | — | CN | claimed |