Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAT2A | P31153 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160665 | 0.83 | MAPK1 (0.53) | GAATSHRPOLBMEN1KMT2A | |
| SCHEMBL28513461 | 0.83 | MAPK1 (0.53) | GAATSHRPOLBMEN1KMT2A | |
| SCHEMBL28512866 | 0.82 | TSHR (0.46) | MAT2ATSHRPOLBMEN1KMT2A | |
| SCHEMBL28518164 | 0.82 | TSHR (0.52) | GAATSHRPOLBMEN1KMT2A | |
| SCHEMBL28513463 | 0.79 | MAT2A (0.47) | MAT2ATSHRPOLBLMNAMAPK1 | |
| SCHEMBL28520871 | 0.79 | LMNA (0.49) | TSHRPOLBMEN1KMT2ALMNA | |
| SCHEMBL28512956 | 0.78 | CYP19A1 (0.53) | GAAPOLBMEN1KMT2ALMNA | |
| SCHEMBL28507326 | 0.76 | GAA (0.44) | GAAMAT2ATSHRPOLBMEN1 | |
| SCHEMBL28519950 | 0.73 | TSHR (0.52) | GAATSHRPOLBLMNASMN1; SMN2 | |
| SCHEMBL28509792 | 0.73 | TSHR (0.46) | GAATSHRPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105359-B | Method for synthesizing indene spiro isoindole [2,1-b ] isoquinoline triketone compound | 河南师范大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-108997339-B | Method for synthesizing isoindole [2,1-b ] isoquinoline-7-carboxylic ester compound | 河南师范大学 | 2021-01-29 | — | — | CN | disclosed |