Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28513461 | 1.00 | MAPK1 (0.53) | MAPK1TSHRPOLBPIM1LMNA | |
| SCHEMBL28516403 | 0.83 | GAA (0.50) | MAPK1TSHRPOLBLMNAKMT2A | |
| SCHEMBL28519950 | 0.83 | TSHR (0.52) | MAPK1TSHRPOLBPIM1LMNA | |
| SCHEMBL28512866 | 0.83 | TSHR (0.46) | MAPK1TSHRPOLBLMNAKMT2A | |
| SCHEMBL28518164 | 0.83 | TSHR (0.52) | MAPK1TSHRPOLBLMNAKMT2A | |
| SCHEMBL28513462 | 0.83 | ALDH1A1 (0.50) | MAPK1TSHRPOLBPIM1LMNA | |
| SCHEMBL28520871 | 0.79 | LMNA (0.49) | TSHRPOLBLMNAKMT2AKDM4E | |
| SCHEMBL28513463 | 0.79 | MAT2A (0.47) | MAPK1TSHRPOLBLMNAPTPN5 | |
| SCHEMBL6824613 | 0.77 | KMT2A (0.51) | PIM1LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL15775852 | 0.77 | KMT2A (0.58) | PIM1KMT2AKDM4EGAAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521310-A | Synthesis method of isoindole isoquinoline spironaphthone compound | 河南师范大学 | 2022-12-27 | — | — | CN | disclosed |