Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522100 | 0.83 | CDK4 (0.44) | MEN1KMT2ANPC1EPAS1MAPT | |
| SCHEMBL4810409 | 0.75 | MEN1 (0.71) | MAPK10MEN1KMT2ANPC1EPAS1 | |
| SCHEMBL29744982 | 0.75 | MEN1 (0.71) | MAPK10MEN1KMT2ANPC1EPAS1 | |
| SCHEMBL4942989 | 0.75 | ALDH1A1 (0.61) | MAPK10MEN1KMT2ANPC1EPAS1 | |
| SCHEMBL16655716 | 0.75 | MEN1 (0.52) | MEN1KMT2ANPC1EPAS1MAPT | |
| SCHEMBL12938273 | 0.70 | ALDH1A1 (0.58) | MEN1KMT2AL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL6951149 | 0.69 | MAPK1 (0.61) | MEN1KMT2ANPC1EPAS1MAPT | |
| SCHEMBL11900688 | 0.69 | MEN1 (0.61) | MAPK10MEN1KMT2ANPC1EPAS1 | |
| SCHEMBL29508937 | 0.69 | PDE10A (0.56) | MEN1KMT2ANPC1MAPTL3MBTL1 | |
| SCHEMBL251800 | 0.69 | PDE10A (0.56) | MEN1KMT2ANPC1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341431-A | Heterocyclic compounds as FGFR4 inhibitors | 齐鲁制药有限公司 | 2021-02-09 | — | — | CN | disclosed |