Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ASPH | Q12797 | 1/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942989 | 0.83 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL29744982 | 0.80 | MEN1 (0.71) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL4810409 | 0.80 | MEN1 (0.71) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL28516641 | 0.75 | MAPK10 (0.48) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL7303310 | 0.75 | TDP1 (0.68) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL7778637 | 0.75 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL16654895 | 0.74 | MAPT (0.55) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL28523405 | 0.74 | EPAS1 (0.52) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL28492301 | 0.74 | MAPK1 (0.58) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL28487623 | 0.74 | L3MBTL1 (0.58) | MEN1KMT2AALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |