Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827916 | 0.73 | ALDH1A1 (0.48) | RAB9AMAPTNPC1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL5054618 | 0.70 | MAPT (0.47) | MAPTALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL6073272 | 0.70 | MAPT (0.47) | RAB9AMAPTNPC1ALDH1A1HTT | |
| SCHEMBL7563004 | 0.70 | ALDH1A1 (0.44) | RAB9AMAPTNPC1ALDH1A1HTT | |
| SCHEMBL17529452 | 0.69 | CTSB (0.51) | RAB9AMAPTALDH1A1HTTKDM4E | |
| SCHEMBL27442187 | 0.69 | SMN1; SMN2 (0.49) | RAB9AALDH1A1HTTKDM4ELMNA | |
| SCHEMBL29639819 | 0.69 | MAPK9 (0.53) | RAB9AMAPTNPC1ALDH1A1HTT | |
| SCHEMBL7089470 | 0.68 | KDM4E (0.45) | RAB9AMAPTNPC1ALDH1A1HTT | |
| SCHEMBL28685228 | 0.68 | MAPT (0.41) | RAB9AMAPTNPC1ALDH1A1HTT | |
| SCHEMBL27357409 | 0.68 | KDM4E (0.53) | RAB9AMAPTNPC1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573915-B | Compounds active against bromodomains | 纽韦卢森公司 | 2020-12-25 | — | — | CN | claimed |