Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523148 | 0.93 | CES2 (0.47) | TP53NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL28516837 | 0.85 | MAPT (0.54) | LMNATP53NPC1RAB9AMAOA | |
| SCHEMBL28531019 | 0.85 | NFE2L2 (0.44) | LMNATP53NPC1RAB9AGAA | |
| SCHEMBL28523005 | 0.85 | HPGD (0.54) | LMNATP53NPC1RAB9AMAOA | |
| SCHEMBL28528084 | 0.81 | MTNR1A (0.53) | TP53KMT2A | |
| SCHEMBL28522680 | 0.81 | CYP1A1 (0.48) | LMNATP53MAOBMAPT | |
| SCHEMBL28522876 | 0.80 | CYP1A2 (0.47) | LMNANPC1RAB9AHPGDMAPT | |
| SCHEMBL5315078 | 0.78 | CES2 (0.47) | TP53NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL28907335 | 0.77 | BCL2A1 (0.50) | LMNATP53NPC1RAB9ARELA | |
| Acetic Acid SCHEMBL28408918 | 0.77 | ACHE (0.71) | ACHELMNANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279743-B | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-112279743-A | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2021-01-29 | — | — | CN | disclosed |