Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | RXRB | P28702 | 4/20 | 0.38 |
| ▸ | RXRG | P48443 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844178 | 0.90 | ALDH1A1 (0.38) | CA5AGAAALDH1A1TSHRNFKB1 | |
| SCHEMBL2731144 | 0.75 | CA5A (0.72) | CA5AGAAALDH1A1TSHRNFKB1 | |
| SCHEMBL3426928 | 0.72 | CA5A (0.49) | CA5AGAAALDH1A1TSHRNFKB1 | |
| SCHEMBL2127191 | 0.71 | PPARD (0.52) | CA5AGAAALDH1A1TSHRNFKB1 | |
| SCHEMBL4597141 | 0.70 | PSEN1 (0.46) | CA5AGAARXRARXRBRXRG | |
| SCHEMBL1679591 | 0.70 | CA5A (0.47) | CA5AGAAALDH1A1TSHRNFKB1 | |
| SCHEMBL5640185 | 0.69 | PPARA (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4461203 | 0.68 | CA2 (0.47) | CA5AGAATSHRRXRARXRB | |
| SCHEMBL6777665 | 0.68 | FFAR4 (0.43) | CA5AGAAALDH1A1TSHRTDP1 | |
| SCHEMBL13111272 | 0.68 | NPC1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |