Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532124 | 0.81 | PPARD (0.39) | PPARDKCNH2GPR119KCNQ3KCNQ2 | |
| SCHEMBL30744362 | 0.80 | TRPV4 (0.37) | PPARDCPB1KCNH2GPR119MAOB | |
| SCHEMBL21491764 | 0.80 | TRPV4 (0.37) | PPARDCPB1KCNH2GPR119MAOB | |
| SCHEMBL21492711 | 0.79 | PPARD (0.42) | PPARDKCNH2KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL21503621 | 0.76 | CA1 (0.42) | PPARDKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL30057190 | 0.76 | CA1 (0.42) | PPARDKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL28908750 | 0.70 | GCGR (0.40) | PPARDKCNH2GPR119MRGPRX4 | |
| SCHEMBL24208607 | 0.69 | CPB1 (0.39) | PPARDCPB1KCNH2GPR119MGLL | |
| SCHEMBL21492945 | 0.69 | CYP11B1 (0.36) | PPARDKCNH2MAOBGRM2 | |
| SCHEMBL28524266 | 0.69 | CYP2C19 (0.38) | PPARDKCNH2MAOBJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |